Literature summary extracted from

Kuijpers, M.J.; van der Meijden, P.E.; Feijge, M.A.; Mattheij, N.J.; May, F.; Govers-Riemslag, J.; Meijers, J.C.; Heemskerk, J.W.; Renne, T.; Cosemans, J.M.
Factor XII regulates the pathological process of thrombus formation on ruptured plaques (2014), Arterioscler. Thromb. Vasc. Biol., 34, 1674-1680.

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.38	Homo sapiens	-	-	-
3.4.21.38	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.21.38	factor XIIa	-	Mus musculus
3.4.21.38	factor XIIa	-	Homo sapiens
3.4.21.38	FXIIa	-	Mus musculus
3.4.21.38	FXIIa	-	Homo sapiens

General Information

EC Number	General Information	Comment	Organism
3.4.21.38	malfunction	genetic deficiency in FXII reduces ex vivo whole-blood thrombus and fibrin formation on immobilized plaque homogenates	Mus musculus
3.4.21.38	malfunction	genetic deficiency in FXII reduces ex vivo whole-blood thrombus and fibrin formation on immobilized plaque homogenates	Homo sapiens
3.4.21.38	physiological function	factor XII regulates the pathological process of thrombus formation on ruptured plaques. Factor XIIa bound to thrombi ensures thrombus stability	Mus musculus
3.4.21.38	physiological function	factor XII regulates the pathological process of thrombus formation on ruptured plaques. Factor XIIa bound to thrombi ensures thrombus stability	Homo sapiens

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Release 2023.1 (January 2023)